Chemistry and Biology

Clarisse Ricci

Clarisse Ricci applies simulations to study biological systems. She holds a Ph.D. in physical chemistry from the State University of Campinas (UNICAMP), Brazil as well as an M.S. in chemistry and a B.S. in pharmacy from the Federal University of Rio Grande do Sul (UFRGS). During her Ph.D., Clarisse used molecular dynamics simulations and other computational tools to study structural and dynamical aspects of PPARgamma, a nuclear receptor that plays a major role in metabolism and is related to “modern life diseases” such as obesity and type II diabetes. Most recently, Clarisse has been a Postdoctoral Fellow in Andrew McCammon’s group at the University of California San Diego, where, among other projects, she developed an implicit solvent method to capture heterogeneous solvation in protein-protein interactions. She has also applied molecular dynamics simulations and other methods to study various biochemical systems, such as NFkB transcription factor interactions with DNA, allosteric mechanisms and off-target effects in CRISPR-Cas9, and proteins involved in the mammalian circadian clock, with a particular emphasis on Casein Kinase 1. In her free time she enjoys rock climbing, dancing (Brazilian) Forró, and playing with her cat, Ziggy.

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